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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMBRA1
All Species:
11.82
Human Site:
S1252
Identified Species:
32.5
UniProt:
Q9C0C7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C7
NP_060219.2
1298
142507
S1252
Q
P
T
L
P
S
S
S
P
V
P
I
P
V
S
Chimpanzee
Pan troglodytes
XP_001163113
1208
132805
S1169
S
P
V
P
I
P
V
S
L
P
S
A
E
G
P
Rhesus Macaque
Macaca mulatta
XP_001112256
1298
142465
S1252
P
P
P
L
P
S
S
S
P
V
P
V
P
V
S
Dog
Lupus familis
XP_540754
1211
132916
L1172
P
V
P
A
P
L
P
L
P
G
T
E
G
P
T
Cat
Felis silvestris
Mouse
Mus musculus
A2AH22
1300
142860
S1253
Q
P
A
L
S
S
S
S
P
V
P
I
P
V
P
Rat
Rattus norvegicus
NP_001127813
1300
142989
S1253
Q
P
A
L
S
S
S
S
P
V
P
I
P
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233289
1300
142720
D1255
G
R
G
T
G
D
L
D
L
P
E
Q
A
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342016
1003
110813
L964
E
G
K
G
S
Q
D
L
T
A
S
S
K
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797133
781
86047
L742
V
N
R
I
I
H
P
L
D
P
Q
Q
R
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
99
89.8
N.A.
95.6
95.9
N.A.
N.A.
83
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
27.6
Protein Similarity:
100
93
99.3
90.7
N.A.
97.1
97.3
N.A.
N.A.
88.9
N.A.
58.7
N.A.
N.A.
N.A.
N.A.
37.6
P-Site Identity:
100
13.3
80
13.3
N.A.
80
80
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
86.6
20
N.A.
80
80
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
12
0
0
0
0
0
12
0
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
12
12
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
12
12
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
12
12
12
0
0
0
0
12
0
0
12
12
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
23
0
0
0
0
0
0
34
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
0
45
0
12
12
34
23
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
23
56
23
12
34
12
23
0
56
34
45
0
45
12
34
% P
% Gln:
34
0
0
0
0
12
0
0
0
0
12
23
0
0
0
% Q
% Arg:
0
12
12
0
0
0
0
0
0
0
0
0
12
12
0
% R
% Ser:
12
0
0
0
34
45
45
56
0
0
23
12
0
0
34
% S
% Thr:
0
0
12
12
0
0
0
0
12
0
12
0
0
12
12
% T
% Val:
12
12
12
0
0
0
12
0
0
45
0
12
0
45
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _